Top Adding - News and Society

Last Monday I was given GoldenEye as I finished paying for a Daily Mail. I wondered what I had actually just bought - was it the paper or was it the DVD?

Have you not

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

iced how newspapers are now giving away more and more, just to get their paper in your hands? How can this be profitable for them? Where did the news go?<

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

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As the cost of technology has fallen so dramatically over the last ten years, so has the price for producing technological goods. Take the now humble DV

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

D. This truly is a marvel of technological creativity - cramming a full, high quality moving picture onto a single disc you can almost it in your pocket. By

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he mid 1990's these revolutionary discs were regularly priced around ?30/$60. Yet people started buying them because of the superior quality and supposed longe

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

vity in relation to tapes.

As more people bought DVD's the price started to drop past the ?20/$40 barrier and you could see the profits translate against the companies

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

who owned the rights to the 'content'.

Bring onto the scene Amazon.com, started by Jeff Bezos, purely for online book retailing which branched into DVDs. Films unava

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ilable in the UK could be imported straightforwardly through the Amazon ordering process. As discs in the US were significantly cheaper than the UK, people were willin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to buy or modify their (hardware) disc player, just to see a film at reduced cost and increased definition.

Where did the cost of producing a DVD drop from ?20/$40 to

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

a freebie in a national newspaper costing between 25p/50c and ?1/$2? The elaborate packaging and artwork have suffered, the physical presence is nothing more than a s

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

liver of cardboard containing a silver disc.

The newspapers rarely list the freebies, as then you would be able to pick and choose.

Recent giveaways were:

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ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

li>The National Geographic in The Telegraph
The Daily Mail with BBC Wildlife with David Attenborough

The Guardian with Posters Of Animals

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

he Independent with 'How To Improve Your English in Seven Days'

The last one was especially noticeable as by mid morning in train stations and towns around London

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

, you wre unable to see a copy of this paper - let alone buy it! For this newspaper, it was unheard of to be sold out!

What is it the papers don't te

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ll you?

Why can't you see the news beyond the headlines?

What are the secrets they keep from you?

I enjoyed the news reports about the Chinese maths test at Universi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ty compared with dear old Pythagoras for remedial British scientists.

Looking at the questions and headlines was designed to give you a headache and a shock, but there

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

was very little explanation. The newspaper didn't even try to enlighten you by printing a detailed answer to either question. The n

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ewspaper is not there to educate you, nor sadly it seems inform you. If you remember the Royal Navy sailors in Iraqi waters, captured by Iran and then selling their st

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ories - you can guess it was just for entertainment.

How they fund their journalism is partially through the freebies, which often have long sponsorship messa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ges before the feature and often through the advertising pages. Just look at the holiday, gardening or home accessories you can now buy through your newspaper..

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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