Top Adding - Computers and Technology

It's been a long while since anyone invented anything truly revolutionary. Mobile phones, email, the wheel, sliced bread, have all been assimilated into our everyday consciousness. Who, for exa

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

mple gives even a precursory glance at footage of the space shuttle taking off these days?Results of experiments in America, however are set to spark debate and excitement throughout the world.

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

Scientists at the Massachusetts Institute of Technology (MIT), have successfully tested a system to remotely deliver power to devices, and believe that the technology can be translated from lab

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ratory to main stream use in a matter of years, entirely doing away with domestic electrical cables.

We had a strong faith in our theory but experiments are the ultimate test," said Assistant

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Professor Marin Soljacic. "So we went ahead and sure enough we were successful, the experiments behave very much like the theory." The system comprised two 60cm diameter copper coils, a transm

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tter attached to a power source and a receiver placed 2m away and attached to a light bulb. When power was sent through the transmitter the bulb lit up despite there being no physical connectio

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

between the two, and was measured as being 40% efficient.

The Science Behind It

The system utilized simple physics. Indeed, Professor Sir John Pendry of Imperial College

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

London claims "There is nothing in this that would have prevented them inventing this ten or even twenty years ago”. It exploits a natural phenomenon called "resonance", in which an object vib

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ates when energy of a certain frequency interacts with it. Think of the way objects in your house vibrate only on certain bass notes when you’re listening to music. It is because the physical c

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

mposition of that object is reacting to the specific frequency of that sound. When two objects resonate at the same frequency they exchange energy. This frequency is particular to those two bo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ies only, and thus has no effect on other surrounding objects. Instead of using acoustic waves, however, WiTricity, as the team has named it, uses low frequency electromagnetic waves. The coil

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s used in the experiment were made to resonate at 10Mhz, permitting energy to flow between them. "With each cycle arriving, more pressure, or voltage in electrical terms, builds up in this coil

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

" explained Professor Pendry.

“Over a number of cycles the voltage gathered until there was enough pressure, or energy, at the surface to flow into the light bulb”. Low frequency electromagnet

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

c waves, which are about 30m long, are thought to be harmless to living creatures. "Ordinarily if you have a transmitter operating like a mobile phone at 2GHz - a much shorter wavelength - then

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it radiates a mixture of magnetic and electric fields," explained Professor Pendry. This is a characteristic of what is known as the "far field": The field which exists at more than one wavele

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

gth from the device. At a distance of less than one wavelength, however, the field is almost entirely magnetic. "The body really responds strongly to electric fields, which is why you can cook

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

chicken in a microwave," said Professor Pendry. "But it doesn't respond to magnetic fields. As far as we know the body has almost zero response to magnetic fields in terms of the amount of pow

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

er it absorbs."

..... And The Future?

The number of ways in which life would change if this technology can be developed into commercial applications is mind boggling. “Th

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

benefit to mankind of eliminating electrical cables goes far beyond the aesthetic and functional gains of the domestic environment” said spokesman Simon Reid. “China’s booming economy has exa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

erbated a world copper shortage, seriously impinging both the pricing and production of power cables. If WiTricity goes on to provide a solution it may prove to be the invention of the century”

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Maintain and grow patient base by carving out a unique brand for your medical practice. This article is useful to medical practices to define their communications strategies.

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