Top Adding - Writing and Speaking

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The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of succes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

sful stories and Hollywood blockbusters are based upon. In fact, ALL of the hundreds of Hollywood movie

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s we have deconstructed (see URL below) are based on this 188+ stage template.

Understanding this temp

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

late is a priority for story or screenwriters. This is the template you must master if you are to succe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ed in the craft.

[The terminology is most often metaphoric and applies to all successful stories and s

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

creenplays, from The Godfather (1972) to Brokeback Mountain (2006) to Annie Hall (1977) to Lord of the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

THER

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

E IS ONLY ONE STORY

THE 188 STAGE HERO'S JOURNEY:

a) Attempts to tap into unconscious expe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ctations the audience has regarding what a story is and how it should be told.

b) Gives the writer mor

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e structural elements than simply three or four acts, plot points, mid point and so on.

c) Gives you a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tangible process for building and releasing dissonance (establishing and achieving catharses, of which

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

there are usually four).

d) Tells you what to write. For example, at a certain stage of the story, the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

focus should be on the Call to Adventure and the micro elements within.

ABRIDGED TIPS, EXCERPTS AND E

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

XAMPLES:

(simply go to http://www.heros-journey

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

.info/ for full details)

*****First Trial Inner Cave - No Going Back*****

A number of things happ

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

en in the Inner Cave of the First Trial. One element is the No Going Back. In Bonnie and Clyde (1967),

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Blanche wants out but Buck (and therefore she) can’t get out because he has killed a man.

*****Demonst

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rating the Magical Gift*****

It is not unusual for the Mentor or Hero to have to demonstrate the Magic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

al Gift. In Brokeback Mountain (2005), Jack uses the gun to shoot the wolf. This often also substitutes

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

as a foreshadow of the coming real use of the Magical Weapon, which is where some obstacle is overcome

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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