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The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockbusters ar

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e based upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL below) are based on this 188+ stage template.

Unde

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rstanding this template is a priority for story or screenwriters. This is the template you must master if you are to succeed in the craft.

[The

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

terminology is most often metaphoric and applies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

) to Annie Hall (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

THERE IS ON

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Y ONE STORY

THE 188 STAGE HERO'S JOURNEY:

a) Attempts to tap into unconscious expectations the audience has regarding what a story is and how i

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t should be told.

b) Gives the writer more structural elements than simply three or four acts, plot points, mid point and so on.

c) Gives you a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tangible process for building and releasing dissonance (establishing and achieving catharses, of which there are usually four).

d) Tells you wh

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

at to write. For example, at a certain stage of the story, the focus should be on the Call to Adventure and the micro elements within.

ABRIDGED

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

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*****Trivial Task*****

During the Period of Desolation, where t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e Hero is not committed to the Journey and Transformation, a Trivial Task sets the Hero on the right course. In Bonnie and Clyde (1967), they ste

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

al another car.

*****Final Conflict: Increased Antagonism*****

Post the Crossing of the Return Threshold and before the Master of Two Worlds an

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

d Selves, a hell of a lot happens that is rarely given mention. The Final Conflict (a metaphor for this stage) follows a distinct process. It is

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

post the initial catharses and the returning confidence of allies, that the antagonist's threat increases. This is often the point of a hand-to-h

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and battle. In Straw Dogs (1971), Tom tries, for the first time, to shoot the door down.

*****Symbolism*****

Symbolism is an underrated aspect

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

f storytelling. The degree of symbolism used in the most successful stories and screenplays is enormous. In Brokeback Mountain (2005), the passin

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

g of the train symbolises Journey. Similarly, the mirror that Jack twist looks into symbolises reflection and dissatisfaction of the Ordinary Sel

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

f.

*****Shape Shifter and Antagonist relationship******

Post the Crossing of the Return Threshold and before the Master of Two Worlds and Selve

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s, a hell of a lot happens that is rarely given mention. The Final Conflict (a metaphor for this stage) follows a distinct process. The Shape Shi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

fter, who has often been close to the antagonist, may be saddened by his (or her) death. In Straw Dogs (1971), Amy is saddened at Charlie's death

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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