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I HAVE A FRIEND who knew a guy who gave him a MIRACLE PRODUCT one day. "Best product in the world," the guy told him. My friend was skepti

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

cal. "Wait until you try it," the guy says.

Oh boy, was the guy right. The product was incredible! My friend felt things he's never felt

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

efore... or since. Colors looked brighter, smells were smellier, thoughts were clearer, much clearer. "This really is a miracle!" my frien

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

d said.

"Told you," was the reply.

A day passed, and the new feeling went with it. My friend went back to the guy for another free sampl

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

. And another. And another. Until one day, the guy's out of free samples.

"But I can get you a couple of ounces for about 40 bucks," the

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

guy said.

My friend is shocked. The price is outrageous! "I had no idea it was that expensive," he said. "I don't have that kind of money

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

"

"Tell you what I can do," the guy told him. "I got people. Rich people. They have truckloads of this stuff. We can sell it to people an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d help split the profits. They'll pay us like a commission. We can probably sell at least enough to cover the cost of OUR product. It'll b

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

like we can get all we want for FREE!"

"But think of this; this product works for EVERYBODY. And I've NEVER met anybody who didn't like

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the stuff. All we gotta do is let them know it exists, and we'll be RICH! What do you think?"

"Sounds good," my friend said. "But there's

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

just one thing. I'm not a salesman."

"Don't have to be," the guy replied. "You've tasted the stuff. It practically sells itself."

"You g

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ot a point there," my friend said. And they were in business.

My friend and his partner are drug dealers. Their product is crack.

Sounds

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

a lot like MLM, doesn't it?

But it didn't at first because we're not selling crack. We're selling real product that helps people. OK, so

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

it's a little expensive. But that's because it's so unique! Besides, you get what you pay for, right? You want the best...

Wait a minute.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Still sounds like a drug deal.

That's because the principles are the same. Just give 'em a taste. (We call it a "free sample".) Let 'em g

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

et hooked on the stuff first. Then they gotta have it. After that, no price is too high to get that feeling.

What "feeling"? In MLM, the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

igh is BIG MONEY. Just think of all you're gonna do with all that loot! Why, just the THOUGHT of it is...

Intoxicating.

See, you're hook

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ed. You got a monkey on your back. But it's not your fault. The people who did it to you were smart. They were ruthless. They even got you

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

FRIENDS to do it to you too... now you've got to do it to someone else, just to support your habit.

Now the good news. You can kick the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

habit and help others at the same time.

It's not that MLM is a bad thing. But it can be done badly. You just have to learn to DO IT RIGHT

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Debt management becomes easier when one takes vow to combine his multiple debts into single one. This can be done through the aid of debt consolidation loan which is a single loan with single rate of interest. This is a unique loan meant for only the purpose of debt management.

Do you live in the state of California? If you do, are you in need of medical insurance, which is also commonly referred to as health insurance? If you are self-employed or if your employer currently does not participate in a healthcare program, you will need to find a health insurance company or provider to do business with. When doing this, there are a number of important factors that you will want to take into consideration.

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