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No matter what type of rejection it is it still hurts. Most people associate rejection with negative feelings since they take it as and an attack on them. There are many different forms of rejection. Love life rejection, friendship, job related. I want to focus on the job related rejection. There are three types

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

of job related rejection and they are idea rejection, position rejection and repetitive rejection.

When your ideas that you have that you have slaved over them to bring them to life are presented to your fellow peers or even your boss or the board of directors rejects your idea. Your first reaction is to take

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t personal because you have lived and breathed this idea from inception to metamorphosis to the fluttering idea that it is. How can one separate these feelings that one has when this happens. Yes it is very hard to do immediately without the right type of mindset. One could allow themselves to develop into a for

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

m of depression from this form of rejection. If one takes the same approach of how people like one another then this will lessen the mental blow that one suffers in this type of rejection. If one knows that not everybody is going to be their friend and that there will always be a few sour apples. If one takes th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s approach to this type of rejection it will lessen the blow knowing that the rejection may not be on the idea itself. The timing of the idea, the funding of the idea or it could be the matching of the idea to the perception of where the board sees the company going. Most of the time the later information is not

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

given to you so that you mind jumps to conclusions and runs amuck. Remembering not to take this type of rejection to heart is one of the hardest steps. File this idea on the back burner and do not get rid of it if you feel that passionate about it. Bring it back out again when you think that time and conditions

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

are favorable.

Position rejection is even harder to handle than idea rejection. Position rejection is more difficult because this is your job advancement and when you are rejected for a position that you are qualified to do. Position rejection almost always comes with no feedback as why you were rejected. So yo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ur mind even runs wilder dreams and more horrified results for the reasons why you where not accepted for the position. If one were to take this type of rejection to heart then one cold simply fall into deep depression and could take a long time to recover from. In my past experienced several of this type of pos

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

tion rejection. The way I combat this type of rejection is a bit different than the idea rejection. The first thing that I do is that I get out of the house and I go somewhere where there will people that I can interact with. This causes your mind not to dwell on the rejection. I normally would go out shopping o

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r I would go out on the town with friends that I would not have to spend lots of money but just to have a good time. The following few days I would go out to a place where I could be alone and be with my thoughts. What I do is simply replay the events back in my head as much as I could remember. Then taking each

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

aspect that I could remember and trying to see if that could have been the reason why the position was not offered to me for that reason. Finally taking each one of these points and using them as a learning tool that I can try to improve on them to make them a positive for the next time I went up for a position.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

The hardest type of rejection to deal with is repetitive rejection. This type of rejection is experienced when a person is rejected time and time again whether or not it is a combination of the other two types of rejections but it can be and is more associated with sales or marketing of products. As a child I

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

earned that this type of rejection was very hard to deal with as a child of about ten years old. I was in the Cub Scouts and each year we sold “Expo tickets” these were tickets that had coupons for various things and were only a dollar each. I would stand out in front of Kmart and sell these tickets for hours up

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on hours some days better than others. I thought that how can someone refuse a little cub scout in his uniform for only a dollar? But you know it they did time and time again. This type of rejection was hard to get over because it was repetitive over and over again for like hours upon hours of selling. Then one

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ay I turned it into a game and the game was very simple in nature. If I sold ten tickets this hour I wanted to sell eleven tickets the next hour. Then form day to day I tried to beat my previous day’s sales and then before long if the person told me “No.” I just thought about it as simply as like if I were at ba

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t and the pitcher threw a strike. I knew that another pitch was just around the corner as well as another at bat. Making it into a game took away the personal feelings that the rejection came with and then my selling of tickets was actually fun and entertaining. As a person would reject me in the sale of a ticke

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

I would then as they would walk off I would add the commentary that an announcer would make at a game “it was a high fast ball straight down the middle and a swing and a miss.” Before too long I had forgotten all about the commentary of the game because I was selling them to almost everybody that walked up to t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he door but not just one in multiples. Making it a game that I played not only made me want to do better but then the idea of failure is common even in baseball. If a batter bats a 500 then he is hitting every other time that he is at bat. This statistic is unrealistic and a very good player may bat a 300 which

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

eans more than half of the time he fails but a only a small part of the time he is hitting. With these statistics a baseball player can and is an excellent player.

When I found the Power Call I noticed that my game was not nearly enough for the mind set that I needed for the marketing and the amount of rejectio

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n that I was getting with my new MLM home-based business. The Power Call is one of the strongest tools in my arsenal now and it prepares me not only for the handling of the rejection that comes with MLM home-based businesses but with the mind set that takes to lead thousands of people in a top-level organization

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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The last in a three part article series about lead capture and email marketing - from a different perspective.

Recent gas price trends have impacted the standard mileage rate allowed by the IRS. Small business owners should be aware of the latest adjustments and take full advantage of all available deductions.

In 1997, and the Taxpayer Relief Act of that year made a dramatic difference in the tax liability of those who sell their own homes.

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