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    The Multilevel Marketing (MLM) industry has exploded to certainly billions if not trillions of dollars per year in total sales. This h
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    as all happened in the last 3 or 4 decades and the growth has especially accelerated in the last decade. Why? Our world is changing ve
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ry rapidly and the rate of change is accelerating. Study history. What once took us decades now takes years, what once took months, no
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    w takes days. And even evident is the continual upgrade of everything. This constant change is unsettling especially for the over 30 c
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    rowd. The athletes who are playing games designed for young boys, are paid millions of dollars annually, redefining the perceived valu
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    es of jobs and the work ethic. Preteenagers play on laptops and cellphones working at the speed of light, amazing their parents. In a
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    word, the answer for this surge of MLM activity in the last decade is UNCERTAINTY. With that in mind, then we can expand that answer.
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    Understanding what is causing the enrollments will allow us to target the correct prospects and offer more persuasive values and benef
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    its. OK, there are really 3 reasons:

    • Money
    • Product
    • Social
    Number One Reason Is Money:

    • need
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    for supplement household income reflecting our present reality of rising prices and fixed incomes
  • need to replace JOB (just ov
  • ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    er broke) income because of
    • job redundancy cutbacks
    • modernization and automation cutbacks
    • production lev
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    el cutbacks
  • outsourcing of jobs
  • quitting
    • pay not enough
    • working conditions not satisfactory
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
  • job satisfaction not satisfactory
  • Number Two Reason Is Product/Service Related

    • product enthusiasm
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    • attribute a significant benefit to product or service
    • some MLM members almost become cult like with very strong loyalt
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ies to the products and services.
  • referral income is a secondary issue
  • personally enjoy the benefits of the produ
  • t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ct
  • want to share benefits of product with others
  • Number Three Reason Is Behavioral

    • social activity
    • l
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ooking for sense of purpose
    • this is becoming a bigger issue as people look to put more meaning in their lives especially e
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    mpty nesters and retired individuals.
  • looking for sense of satisfaction and contribution
  • team atmosphere and soci
  • .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    al interaction
  • like a hobby
  • filling time
  • filling time after retirement
  • OK, we have identified most of
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    the reasons that people join MLM programs. In the next article we will investigate what happens to them after they join a MLM program


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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