Top Adding - Real Estate

A few years back we decided to sell our house and move on to a new area.

One of the first things

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

we did was put a signboard on our window with our telephone number on it so that anyone interested

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

could call us and we could show them the house.

The result was terrible. Estate agents kept on c

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

alling saying that they had clients for our house. First you think 'hey, that is pretty cool' so t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he estate agents came to our house by the dozen taking photos and measuring the rooms. We thought

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e had the house sold.

Months passed and every week one or two newly established estate agents wou

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ld come to our house and do the same thing. What was funny is that none of them ever came with any

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

clients.

So we thought that maybe the house was too expensive, so we dropped the price and actua

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lly spent our time and money calling all these Agents telling them about the price change.

Then w

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e did get clients through them, but I will never understand why we got the same clients through va

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ious Estate Agents. If they had already seen the house then why come with another Agent to see it

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

again?

Well it seems this is pretty the norm. They see the house with one and then visit another

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

because they know the Estate Agents usually have the same houses for sale and see it again and try

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to renegotiate the price.

Why do Estate Agents allow this? Every time we negotiated the price be

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

cause the Estate Agent said that someone who saw our house wanted to buy it, instead of selling it

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

we would see the same clients with another Estate Agent. So all that was happening is that we wer

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e negotiating with one Agent the price that had already been negotiated with another Agent and the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y were from different companies.

My advice to anyone selling their house is find an established a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

gent and stick to him. Putting the house for sale in a lot of agents will only gave us headaches a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nd if you do sell the house be prepared to sell it for much less than what you initially asked for

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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