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Is there a song that gets to you, so much that you get goose bumps all over, and aren’t really sure why? Except maybe th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

at it’s an awesome song?

Well, today, Don’t Look Back (Boston, 1977) was that song for me.

All day I’ve been wondering

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

why… I mean, I haven’t been able to stop listening to it since I got up this morning. Now I think I know why.

Maybe it

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

had something to do with the teleconferences that we held recently, or the presentation we did last weekend, with many

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

conversations to follow. Let’s just say the past week has brought even more than our usual networking load and hearing l

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ots, and lots more, of stories from fellow investors.

It’s clear now more than ever that the patterns followed by many

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

real estate investors are not working. It’s time to change directions. Too much negative cash flow, too many confusing b

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

uilder contracts, too much lost earnest money. Deals gone bad that were never really deals to begin with. Techniques and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

plans that may have worked two years ago (quick flips are a good example of that) are now as unrealistic as good music

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is in today’s world. (Hence, needing to stick with real music from my childhood in the 70’s.)

There’s no doubt that the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

changes in the lending world, as well as copious inventory of new building developments, must lead to changes in the wa

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y that many investors do things. So, why not start now? Don’t look back. Regrets don’t help, and may keep you from movin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

g forward.

From now on, don’t do any deals that don’t pay you up front. No more negative cash flow! No more alligators!

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Leave them in the swamp where they belong, not bleeding your wallet. Don’t allow nitwit agents to talk you into non-dea

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ls. Who’s going to be responsible for the payments, you or them? Enough!

Don’t look back. It’s time to move on. You’re

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

smarter, wiser, than all that. It’s time to focus on making money. Real estate is about so many things: a roof over your

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

head, tax advantages, commercial uses, speculative building, etc. etc. It can be overwhelming at times. How about for n

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ow, just think how it’s going to make money for you?

I've said it before, and I’ll say it again: if real estate investi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ng has not yielded you results you wanted, decide whether you want to make money or not. (Many people are scared to deat

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

h of money.) Once you decide that, your life will never be the same. You’ll start getting deals — that really ARE deals!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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