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In the UK, everyday more and more novice landlords are tempted into the buy-to-l

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

et investment sector not only by a range of new and competitive products by the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ortgage lenders but also by the success stories of the other property investors.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

The buy-to-let mortgages are now a lot easier to obtain and a lot more competit

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ve compared to five or six years ago.

Although traditionally the lenders requir

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d a 130% rental to mortgage repayment ratio to secure a margin of safety during

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the vacant periods, some lenders are now allowing the predicted rental income to

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

be 100% of the mortgage repayments. There are even products out there that requi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e no indication of rental income.

The financial experts seem to be divided abou

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

these new products in the marketplace. Some experts argue that a lot of the nov

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ce landlords may be badly exposed by further interest rate rises that are widely

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

forecasted for the rest of 2007 and potentially in 2008 too. According to this

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

roup of experts this situation is creating a lot of high risk investors that wil

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

be adversely affected by even marginal interest rate increases and this could p

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tentially be the downfall of the buy-to-let investments in this country. Whereas

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the others argue that "when used properly by the experienced landlords", these p

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

roducts do offer a lot of choice and flexibility, which can only strengthen the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

uy-to-let market.

Overall, it is down to the individual landlord to decide how

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

uch risk they wish to take but our advice to any novice landlords would be to se

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

k independent financial advice from the experts before making any such decisions

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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