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    On floor duty this morning and took a call from an interesting young lady. She is very intelligent and well-spoken, but the way she is g
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    oing about purchasing her home is going to lead to bad feelings.

    But it isn't her fault, she was doing what she thought she needed to d
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    o -- especially on their limited budget.

    So, I'm going to pass along the same advice that I gave her this morning on how you should sel
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    ect a buyer's agent.

    First, calling on signs is fine. But you have to understand what you are doing when you pick up the phone. By enga
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ging in conversation with the selling agent, you are a customer for the agent and receive the basic required courtesies. However, you ha
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ve to remember that the seller is that agent's client. And as a client, that agent owes a much stronger level of responsibility to that
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    seller than to you as a buyer.

    What does that mean?

    Calling on signs will always put you at a disadvantage.

    All list
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ed properties have a seller's agent.

    The seller's agent is of course going to be nice to you. They are hoping that if you don't become
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    the buyer for this home, that they can become your buyer's agent.

    So how do you find an agent?

    As a new agent, the la
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    st thing I want to do is use the "r" word. But the best place to get deal is a referral from a friend, but be sure to find out why they
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    are passing along the name. Is it because of how they worked with this agent? Or simply that they see this person's name all the time?

    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    And once you get a couple of agent's names, then sit down and interview them. Find out how they are going to help you -- and if there is
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    a good fit. Remember, buying a home is one of the most expensive decisions you will make. You need to trust this person is going to hav
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    e your desires at heart.

    But doesn't that cost me more money?

    Nope. Not a dime. When the home was listed, there is a
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    form on the listing agreement that dictates how much, if any, the selling broker will pay to the buying broker for bringing you to the t
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ransaction.

    Now being totally honest, you will run into one situation where you will be asked about commission when you sign a purchase
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    contract. And that is if you purchase a HUD home. In this case when you sign the purchase contract, you can allocate 1-5 percent of the
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    purchase price to your buyer's agent. Understanding that the allocation will directly result in you paying more for the home.

    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    Finally

    The pay that you will give to a buyer's agent will be the same whether you call an agent before you go through your fi
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    rst house, or the day before you write the contract.

    So get someone in your corner from the beginning -- and allow them to work for you


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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