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    You have lived in rented accommodations long enough. You want to buy a house and make it a home for you
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    and your young family. You consult your friends, you consult property agents. You consult websites and g
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    through property advertisements. And all along you feel uneasy that you are missing out on something.

    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    t gradually dawns on you that you are missing out the element that matters the most – the feeling of bel
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    nging that you would want in the new environments. All your talk with the agents, all discussions on bud
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    eting, all the viewings are very superficial.

    Once you have chosen the area in which you would like to
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    live (convenient for commuting to work) and have started considering some houses in that area, you would
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    like to get a feel of the neighborhood, see the civic amenities existing in that area. You would like to
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    be sure your family will not only be secure but feel secure too. You would like to know what sort of nei
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    hbors your wife will have – friendly, helpful, snobbish, snooty, garrulous, intruding or what…

    Why don’
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    you take a stroll down the neighborhood, walk over to the local market place and see what sort of crowd
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    s you see. Drop in on some neighbors just to say “Hello!” and you sure will learn a lot of the local gos
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ip and atmosphere too. You will also get an idea of the local crime scene if you steer the conversation
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    n the right direction discreetly.

    Drop in on the local police station to get a feel of the security ang
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    e.

    You would also like to know about the public transport facilities in that area, the local GPs, the b
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    nks in the vicinity.

    By now you would have been able to size up that environment of the locality that y
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ou would never have been able to do by talking to any umber of agents. You could repeat the routine unti
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    you feel comfortable with the locality. After that the rest of the issues related to the property would
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    be easy to deal with.

    A word of caution: do not disclose your findings to the property agent; he will n
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    t lose the chance to use your satisfaction about the locality to your disadvantage in price negotiations


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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