Top Adding - Real Estate

If the sellers are not pleased with your offer, they may turn it down outright or g

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ive a counteroffer. So, let’s say that the sellers agree with all of the terms in

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

our offer except for the price. The sellers may send your offer back with your pri

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ce marked out and suggest a higher price.

Or, I will give a different scenario. L

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t’s instead say that the sellers are pleased with your offer overall, but you asked

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

for them to do too much – like asking for a long list of repairs to be made, makin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

a lower offer on the price, and requesting that you sell the house you are living

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

in now before buying the sellers’ house. If the sellers don’t outright reject your

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

offer, they may choose to only allow one of these requests in a counteroffer.

If t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

he sellers feel that you are going to be too demanding and too difficult to work wi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

h, they may turn down your offer. So, when you make an offer on a home, try to be

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

easonable with your requests. Your real estate agent will be able to talk with you

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

and try to help get you what you want while also making a good offer in order to s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

cure the house you want.

Your agent can also see how long the house has been on th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e real estate market and find out if there have been any other offers made on the h

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

me. So, if the house has been on the market for a while, you may be able to negoti

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ate a lower asking price. Depending on the market history (and some other factors,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

like the sellers’ expectations), you may be able to talk down the sellers three per

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

cent or so of the asking price. And, as I mentioned earlier, your agent will be ab

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e to guide you through making an offer so that you can get the home you really want

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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