Top Adding - Real Estate

While we all hope that a sale closes smoothly and the outcome is fair to both parties involved, the truth is that when a home is being sold, both

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

the buyer and the seller want to get the best deal possible. Unfortunately, it usually just isn't possible for the seller to get the most they p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ossibly can for the home and a buyer to also be getting a great bargain. During negotiations, both parties will be observing their own agenda. Kn

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

owing the common negotiating tactics will help you keep the outcome fair, whichever side of the deal you are on.

For a buyer, price whittling ca

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n lead to a lower sale price, but it can also mean a missed opportunity. If you keep grinding the seller with a low offer, and expect a whole bun

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ch of "extras", don't be surprised if they go with another offer. For sellers, be aware that accepting a lower offer that has no strings attached

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

may in fact make you more money in the long run than a higher offer that requires you to pay closing fees or finish renovations.

If a couple is

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

buying or selling a home, they may play off each other to move the transaction in their favor. For example, one spouse may convince the seller th

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e sale is imminent, then request more time to talk to the other spouse. After a time, a lower offer may be presented on the excuse that the other

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

spouse isn't as sure. The fact is, if someone wants a house, they will buy it. If they don't want it, why would $5000 less make it any more appe

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

aling? To avoid having spouses play off each other in negotiation, be sure to present offers to both of them simultaneously. If only one spouse s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hows up at a meeting, assure that they have decision making authority. If they don't then the meeting won't be as productive. Try to avoid this s

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

cenario as it delays the process.

Sometimes, a third party must be consulted before any decision making can be done. Parties such as investors,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

loaners, co-signers or even advisors may be required to give the Okay before a buyer will make a decision. Be sure to determine this early on. If

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

a third party is genuinely necessary, this will be a factor that slows down the negotiation process quite a bit. If one is not really necessary,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a buyer may be using it as an excuse to manipulate negotiations.

If a seller is stalling on accepting your offer, you need to remember that you

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

have the right to revoke your offer. While this is usually a last resort, if your finances require a speedy closing, there is no need to get stuc

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

k in one offer. If you let them know you don't have time for it, and are willing to back out of your offer, they may just change their minds and

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

accept what you've offered them.

Both parties in a real estate transaction need to recognize what is fair and just be honest about it. While no

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

one party can win it all, a fair price can easily be agreed upon if one knows how to avoid manipulation and maintains an honest negotiating style

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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