Top Adding - Real Estate

Five practical areas to discuss with your designer or to keep in mind when plan shopping for your new home project. Here they are and not in any part

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

icular order.

Roofline-The steeper the roof the more the cost in most cases. If you have noticed lately, there are allot of new home developments wh

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ere the roof of the home is quite high and large. This is usually because the home itself is a smaller square footage and the roof makes it look bigg

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r. Always remember that the roof area equates to more sheets of plywood, more shingles and more labor. Gable roofs are less expensive than hip or cot

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

tage roofs. I suggest a 6/12 roof slope or less to keep the roof cost on budget. You might want to discuss this with your designer.

Windows/doors-Th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s is a crucial part of design. Let’s look at a few things that effect overall cost. Obviously the amount of windows, size of the windows, whether the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

y open or not, as well as rounded top glass will effect your budget. The average home usually has 12-15 windows. Opening or venting windows cost more

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

than a fixed or picture window. Rounded glass can cost as much as double the cost of an average window so use them sparingly. Wood windows usually co

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

st more than conventional vinyl (PVC) windows. A door example is a double French exterior door is more expensive than a standard patio door.

Wall he

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ghts-The trend in the new home building industry today is to design and build with 9 foot walls and ceilings. This gives a home larger feel vs. a tra

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ditional 8' wall height. This will affect the cost of the finished home as there is more wall area for drywall, siding, etc. In a 1500 square foot ho

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

me or less, I would recommend 9' ceilings to take advantage of the space. Two story walls, referred to as balloon framing, really adds to the cost of

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

framing.

Vaulted ceilings-This is a raised ceiling in the home, usually going to a peak. It is a great idea to integrate into the design if you want

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

the cost of standard 8 foot high walls with the higher vaulted ceilings giving the perception of a lager space. There are typically two types of vau

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ted trusses used in a new home design. The first on is the Scissor truss vault which gives a gentler raised ceiling and is less expensive, and the se

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

cond is a cathedral vault which typically is a full height vault with a ridge beam. You see these allot in a Chalet style cabin. (steeper vault)

Fou

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

dation-A full concrete foundation (8 foot basement) in most cases will cost more than a crawlspace or slab foundation. If you don't have allot of sto

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rage designed into the home, a full foundation may be required and is also a great re-sale feature. A sloped lot may accommodate a day-lite or walkou

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

basement option as well. Basement development, as well as extra space over a garage, are the least expensive ways to add square feet to a home.

So

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

if you are about to get plans designed for your new home or just looking for a plan online, keep this five points in mind. Your wallet will thank you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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