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As a society we are fast beginning to realise that what we do has an effect on the environment around us. Upon realisation of this fact we start to wonder what we

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

can do as our small contribution. Especially considering the carbon footprint for the average UK household which currently rests at 26,316 Kg of CO2.

Environmen

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

talists believe that to halt Global warming we each need to shave 2,500 Kg off this amount a year, a figure nearing 10%. If we look at some of the key areas of CO

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

2 Production in the household we see this is certainly a possibility; Gas, coal and oil account for 3,876 Kg, electricity 3,127 Kg and use of car 2,600 Kg.

Thes

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e are certainly figures we can certainly do some work at decreasing. Take for instance your car; there are many options to avoid using it unnecessarily, try walki

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ng or using a bike if your journey is a very close one. Alternatively use public transport; a bus for example will save much CO2 production. Another suggestion

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

in this area is eco-friendly car insurance. This is much cheaper than at its inception, with good deals now being found through many companies. These companies w

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rk by offsetting your CO2 production, investing money into green schemes such as; forestry, energy saving and renewable energy schemes. Consider buying a car with

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

a smaller engine; be sure to check to consumption figures as not all small engines are as economical as you’d think. Another possibility is having your car conve

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rted to dual fuel or buying a diesel engine as this is much more economical on a fuel consumption basis. Who knows you might even save money on your motor insuran

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ce policy in the process.

In terms of carbon fuel reduction, such as coal, gas and oil, you can help reduce this by making your home more energy efficient. There

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

are many way’s you can reduce your heating bills and save on your CO2 production. Are you windows double glazed? Is your loft insulated? Do you have cavity wall

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

insulation? Do your appliances have good energy saving ratings? If the answer to any or all of these is no then you can make a big saving on CO2 production and ind

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eed your utility bills by addressing these issues. Several insurance companies are now offering Eco house insurance amongst their policies, again using a percenta

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e of funds to offset CO2 production. If you can find a company offering this whilst looking to renew you policy you can further shave more carbon emissions by the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

offsetting action it offers.

On closer inspection of the ethics of these companies they appear to be sound. They work out how much the carbon emissions will be

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

on average for a vehicle or household and then aim to offset somewhere in the region of 20%. This is done by donating money to schemes which are developing altern

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

atives to fossil fuels and forestry schemes whereby many new trees are planted which helps to absorb some of the carbon emissions in the short to medium term. If

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

you consider that 20% of your average carbon emissions for your car works out at 520 Kg you are well on your way to shaving that 2,500 Kg of your household carbon

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

footprint. With the added reduction from making your home more environmentally friendly you should be virtually there.

It’s not that hard when you think about it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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