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Personally, I prefer the one-to-one, head-to-head transaction of collector to dealer. Not only is there a give and take but also an exchange of ideas and information and a certa

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

in camaraderie that can add to the pleasure of collecting. However, there's no denying that numismatics is heading headlong into the Electronics Age.

Two recent developments ad

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

to the already existing systems. Perhaps the most significant is Teletrade, which utilizes the telephone to expedite transactions.

Bernard Rome, founder of the firm, says: "We

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

are not a dealer or an investment firm. We are simply an exchange for bringing together buyers and sellers. In this respect, Teletrade is a numismatic equivalent to the New York

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Stock Exchange."

Participants use the system by calling a toll-free number and giving the computer a special code. Callers then will be given the lowest asking price and the hi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ghest bid price for coins they inquire about. Only coins graded by the American Numismatic Assn. Certification Service will be traded on Teletrade. Participants will pay $20 mon

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hly for Teletrade's services. For information, contact Teletrade at 375 Park Ave., New York, N.Y. 10022 or telephone (800) 223-5554.

Another recently announced service is the I

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ternational Collectors Network, which utilizes a computerized bulletin board for buying and selling everything from coins to baseball cards, post cards, old books, autographs an

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

other collectibles. Computer bulletin boards are not new, but utilizing them in an organized fashion as a buy-sell outlet offers yet another electronic dimension for those with

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

personal computers. For information, contact the International Collectors Network, 2265 Westwood Blvd., No. 801, Los Angeles, Calif. 90064; telephone (213) 204-0646.

Question:

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Could you please advise me of the value of U.S. 1865 3-cent and 1868 2-cent coins? I rarely have seen these coins. Why is it they appear unpopular with collectors?-S.S.G.

Answe

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

: Your 3-cent piece, undoubtedly nickel rather than the rare silver of the same date (but different design), is one of more than 11.3 million issued. Your 2-cent piece is one of

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

more than 2.8 million. Both are worth $3 each and up. But the point is that they're in plentiful supply and, as you indicate, unpopular with collectors. Well, I'm not sure of th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eir unpopularity, exactly, especially with type collectors. But it's true that certain denominations will appeal to more collectors than others. Right now, silver dollars and go

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d are big. Next year it could be commemoratives, and, who knows, maybe after that the 3-cent and 2-cent denominations will have their day. Some of it has to do with collector ta

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tes. Some of it is due to promotional manipulation.

1987 Coin News:

A souvenir card commemorating the American Numismatic Assn.'s midwinter convention in Salt Lake City, Wedne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

day through March 2, is being issued by the Bureau of Engraving and Printing. The card depicts the reverse of a Series 1901, $10 U.S. note (pictured). The central design feature

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s an allegorical vignette of "Progress" in the form of a woman. Souvenir cards cost $4 by mail. Order item No. 920 by check or money order made payable to "BEP." Send to Bureau

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

f Engraving and Printing, Mail Order Sales, Room 602-11A, 14th and C streets, S.W., Washington, D.C. 20228.

Veteran Los Angeles and Orange County coin dealer Joel Rettew

Curre

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t Location:

Joel Rettew 23685 Moulton Pkwy B-1 Laguna Hills, CA 92653 949 609 0110

This is an article from the LA Times where Mr. Rettew was a contributer for over 17 years

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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